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Targeted Therapy, 
Guided by Precision Expertise 
at Apollo Athenaa

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What is 
Targeted Therapy 
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Targeted therapy is a major breakthrough in modern oncology, offering cancer treatment that is not only more effective but also more personalized and often better tolerated than traditional chemotherapy. As a central pillar of precision oncology, targeted therapy focuses on the unique molecular features of a patient's tumor to guide treatment decisions.

Unlike conventional therapies that affect both healthy and cancerous cells, targeted treatments are designed to disrupt specific genetic mutations or signaling pathways that allow cancer cells to grow and survive. This precision enables the expert medical oncologists at Apollo Athenaa to deliver more focused care with improved outcomes and fewer systemic side effects.

How the 
Treatment Works
At Apollo Athenaa, targeted therapy begins with advanced molecular testing to uncover the specific genetic or protein-level changes driving each woman’s cancer. These insights guide the selection of therapies that directly act on those abnormalities.
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Targeted therapies act on molecular abnormalities such as:

  • Gene mutations (like EGFR, ALK, BRAF, KRAS)
  • Protein overexpression (like HER2)
  • Abnormal signaling pathways (like PI3K/AKT/mTOR) 
     

The two main forms of targeted therapy include:

  • Small molecule inhibitors: These enter cancer cells and block internal signals essential for tumor growth.
  • Monoclonal antibodies: These engineered proteins attach to specific targets on the surface of cancer cells to block growth signals, mark them for immune attack, or deliver toxins directly to the tumor.

 

Targeted therapies are often taken orally or administered via intravenous infusion. Their use depends on the presence of actionable biomarkers, which are identified through molecular and genetic testing of the tumor.

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When Targeted Therapy 
Is Recommended
Targeted therapy is used in a variety of clinical scenarios, including:
Driver Mutations

First-line treatment for cancers with known driver mutations (e.g., EGFR-mutated lung cancer, HER2-positive breast cancer, BRAF-mutated melanoma).

Post-Resistance

Used as second-line or subsequent therapy when standard treatments fail or resistance develops.

Combination Use

Given along with chemotherapy, immunotherapy, or other targeted agents to enhance treatment effectiveness.

Tumor-Agnostic

Used when a specific mutation (such as NTRK fusion or MSI-H) can be targeted regardless of where the cancer started.

Key 
Advantages
Experience the benefits of advanced targeted care tailored to your needs. At Apollo Athenaa, our approach ensures accuracy, comfort, and better treatment outcomes at every step.
Precision and Personalization
Therapy is chosen based on tumor-specific genetic or protein alterations, ensuring treatment directly targets the cancer’s underlying biology.
Improved Response
Targeted therapies act on precise pathways, offering higher efficacy in select cancers while generally causing fewer, more manageable side effects than chemotherapy.
Higher Efficacy in Select Cancers
Targeted therapy can significantly prolong survival and disease control in cancers that carry known actionable mutations.
Tumor-Agnostic Potential
Certain drugs can treat cancers based on mutation rather than location, expanding treatment options for rare or difficult-to-treat cancers.
Side Effects Of 
Targeted Therapy
At Apollo Athenaa, targeted therapies are selected with precision and closely monitored to ensure patient safety. While they are generally better tolerated than chemotherapy, they can cause specific side effects related to the pathways they inhibit.
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Side effects include:

  • Skin rash and dryness
  • Diarrhoea
  • Fatigue
  • Elevated blood pressure
  • Changes in liver function or blood counts
  • Nail or hair texture changes
     

At Apollo Athenaa, all patients receiving targeted therapy are closely monitored through regular labs, symptom checklists, and scheduled reviews. Early management of side effects allows patients to continue therapy with minimal disruption.

Continuum of Care
At Apollo Athenaa, long-term management of targeted therapy is proactive and personalized. While many patients achieve durable responses, resistance mechanisms like secondary mutations or pathway bypass can emerge.
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Periodic imaging to assess tumor response and detect early signs of progression

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Routine blood tests to evaluate liver, kidney, and blood count changes associated with specific drug

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Re-biopsy or liquid biopsy during progression to identify emerging mutations or new therapeutic targets

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Transition to combination therapies or next-generation inhibitors based on evolving molecular insights

Frequently Asked Questions
Will targeted therapy affect my skin or hair, and can I manage these changes?
01

Some drugs may cause dryness, rash, or texture changes. At Apollo Athenaa, dermatologists work alongside your oncology team to create preventive and soothing skincare routines.

Can targeted therapy impact my menstrual cycle or hormones?
02

Certain targeted agents may cause mild hormonal changes. Apollo Athenaa monitors menstrual and hormonal patterns and coordinates care with gynecology specialists as needed.

Are oral targeted therapies safe if I have young children at home?
03

Yes, as long as they’re stored and handled safely. At Apollo Athenaa, nurses guide mothers on safe medication storage and handling practices.

What should I do if I miss a dose of my targeted therapy?
04

Do not double the next dose. Contact your care team. Apollo Athenaa’s pharmacists advise the correct next step based on the drug involved.

Are there foods, drinks, or supplements I should avoid?
05

Some targeted therapies interact with specific foods or supplements. At Apollo Athenaa, oncology pharmacists review your diet and supplement list to help avoid harmful interactions.

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